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针对主要表现为主动脉反流的J-瓣膜移植的新的经导管主动脉瓣置换系统及早期结局

A New Transcatheter Aortic Valve Replacement System for Predominant Aortic Regurgitation Implantation of the J-Valve and Early Outcome

来源:Scopus 发布时间:2016-2-17
作者:Wei, L., Liu, H., Zhu, L., Yang, Y., Zheng, J., Guo, K., Luo, H., Zhao, W., Yang, X., Maimaiti, A., Wang, C.
机构: 复旦大学中山医院上海心血管研究所 心血管外科
期刊: JACC: Cardiovascular Interventions2015年12月14期8卷

Objectives This study introduces a newly designed transcatheter aortic valve system, the J-Valve system, and evaluates its application in patients with predominant aortic regurgitation without significant valve calcification. We also report the early results of one of the first series of transapical implantations of this device and aim to offer guidance on the technical aspects of the procedure. Background Transcatheter aortic valve replacement (TAVR) has been widely used in high-risk patients for surgical aortic valve replacement. However, the majority of the TAVR devices were designed for aortic valve stenosis with significant valve calcification. Methods Six patients with native aortic regurgitation without significant valve calcification (age, 61 to 83 years; mean age, 75.50 ± 8.14 years) underwent transapical implantation of the J-Valve prosthesis (JieCheng Medical Technology Co., Ltd., Suzhou, China), a self-expandable porcine valve, in the aortic position at our institution. All patients were considered to be prohibitive or high risk for surgical valve replacement (logistic EuroSCORE [European System for Cardiac Operative Risk Evaluation], 22.15% to 44.44%; mean, 29.32 ± 7.70%) after evaluation by an interdisciplinary heart team. Procedural and clinical outcomes were analyzed. Results Implantations were successful in all patients. During the follow-up period (from 31 days to 186 days, mean follow-up was 110.00 ± 77.944 days), only 1 patient had trivial prosthetic valve regurgitation, and none of these patients had paravalvular leak of more than mild grade. There were no major post-operative complications or mortality during the follow-up. Conclusions Our study demonstrated the feasibility of transapical implantation of the J-Valve system in high-risk patients with predominant aortic regurgitation. © 2015 American College of Cardiology Foundation.

 

通讯作者:Department of Cardiovascular Surgery, Shanghai Cardiovascular Institution, Zhongshan Hospital, Fudan University, No. 180, Fenglin Road, Shanghai, China
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